Following the 1-1 draw at Everton last weekend, Toby Alderweireld, Eric Dier, Tom Carroll and Christian Eriksen are the only players who keep their place for Spurs’ FA Cup meeting with Leicester.
Danny Rose captains the side, while Heung-Min Son leads the front line with Harry Kane rested.
Nabil Bentaleb only makes the bench. Andros Townsend isn’t even among the substitutes.
Leicester have also made a number of changes, likely due to the importance of Wednesday night’s Premier League meeting between the sides.
Here’s how Twitter reacted to all the team news.
Danny Rose captain well done son ????
— Kenny Palmer (@KennyPalmer) January 10, 2016
A bit of rotation in there, but I'm liking the look of that XI. Nice to see Wimmer given a chance, would've liked to have seen Nabil start.
— Spurs In The Blood (@SpursInTheBlood) January 10, 2016
Goodbye my lover, goodbye my friend, you have been the one, you have been the one for me pic.twitter.com/P5MfYGbx3Q
— Billie (@Billie_T) January 10, 2016
We all want to win every trophy but reality is that you can't do that by playing the same line up every game.
— Alan (@hotspur423) January 10, 2016
#coys Absence of Bentaleb is a big talking point. I've heard rumblings about an unwillingness to fight for his place — hard to ignore now.
— Dan Kilpatrick (@Dan_KP) January 10, 2016
Thrilled to see Rose captaining the side – testament to his character & maturity. Always speaks well off the pitch, clearly well thought of.
— Chris Miller (@WindyCOYS) January 10, 2016
Never have and never will see the point in playing your reserve keeper without it being necessary.
— Ben (@InsideN17) January 10, 2016
So long, Andros.
— Charlie Parrish (@charlieparrish) January 10, 2016
If Bentaleb was deserving of a start, he would be getting one. Simple as that.
— Ian M. Walker (@ForgottenLibero) January 10, 2016
OK, who had "Tom Carroll first name on the teamsheet" and "Danny Rose captain" in the signs of the apocalypse sweepstake?
— Bankrupt (@bankruptspurs) January 10, 2016
Bit of a pity we couldn't rest Alderweireld and Dier as well but that's some good rotation from Pochettino. Go on Onomah! Rose skipper too!
— Jay Jaffa (@jayjaffa) January 10, 2016
Pochettino is using Eric Dier as his test subject in an experiment to find out just how far the human body can be pushed, isn't he?
— Raj Bains (@BainsXIII) January 10, 2016
Expected changes. Would haven liked to have seen Bentaleb in there. Good to see Wimmer get a start.
— The Fighting Cock (@LoveTheShirt) January 10, 2016
Interesting that Winks is on the bench. Thought Bristol City were sniffing around him. Sure they'd not want him cup tied.
— O'Boogie (@drwinston001) January 10, 2016
Fantastic to see Pochettino's continued trust in youth with giving Onomah a start & also giving Rose the captaincy, now for the win! #THFC
— Ricky Sacks (@RickSpur) January 10, 2016