Jose Mourinho has recalled Davinson Sanchez, Heung Min Son and Lucas Moura in making three changes for this afternoons north London derby.
The Spurs boss remains without the injured Juan Foyth and Dele Alli, whilst Eric Dier serves the second of game of his four-match suspension and is once again sidelined.
There is good news for the Portuguese, who has been able to name Japhet Tanganga on the bench for the first time since the restart after missing the previous five matches since the Premier League resumed.
Sanchez replaces Jan Vertonghen in the only change to the back-four, whilst Lucas Moura and Heung Min Son return to the side and join Harry Kane in attack.
Harry Winks, Moussa Sissoko and Giovani Lo Celso start in midfield together – with Tanguy Ndombele among the substitutes.
Starting XI: Lloris, Aurier, Sanchez, Alderweireld, Davies, Winks, Sissoko, Lo Celso, Son, Moura, Kane.
Subs: Gazzaniga, Vertonghen, Tanganga, Sessegnon, Skipp, Ndombele, Gedson, Bergwijn, Lamela.